The project

What is anorexia nervosa?

Anorexia nervosa is an eating disorder that can endanger the life of those affected. The disease is manifested by a refusal to maintain the weight or the fear of gaining weight, until to have a distorted image of own body. A person is defined anorexic when the body weight falls below 85% of the expected according to age, sex and height. In Italy, there are more than 3.500.000 people, 20% of which teenagers, who suffer from eating disorders. Anorexia nervosa, is the first cause of death among young Italian girls aged between 12 and 25 years old. It represents a real socio-health alert. Surely, it is a disease that results from a state of emotional and psychological distress: those who suffer from anorexia nervosa feel unable to defend themselves from pain, lack of affection or have internal conflicts, disappointments at work, home, school, difficulties in romantic relationships. However, it is not just a psychiatric illness, but there are important biological implications as well. Prolonged fasting and an insufficient nutrient supply contribute to alterations in cellular energy metabolism that coincide with an increased production of free radicals and oxidative stress. The aim of our research work will be to demonstrate how these cellular changes, could be used as a new target for treatment.


LINK

https://www.youtube.com/watch?v=HkIPLmkDbFk
http://laprovinciapavese.gelocal.it/pavia/cronaca/2016/02/11/news/al-mondino-i-cani-per-guarire-l-anoressia-1.12943680
http://guidominciotti.blog.ilsole24ore.com/2016/02/09/quattro-zampe-contro-lanoressia-un-progetto-di-pet-therapy-parte-a-milano/
https://www.facebook.com/ricercascientificanoressia/

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  • The name of the donor will be reported in the scientific publication to be published with the results obtained

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Goals

Our aims:

1) patient recruitment, formulation of inclusion and exclusion criteria, food diary, development and adjustment of extraction protocols from biological samples and data analysis.

2) collection of clinical and behavioral data from AN patients and healthy control subjects, collection of blood and urine samples, analysis and evaluation of oxidative stress and hormone profile. Data analysis to correlate the level of oxidative stress and the antioxidant molecules between AN patients and healthy subjects; moreover, results will be correlated with the severity and the course of the disease. According to the results obtained during the study, a nutraceutical will be evaluated in order to assess a possible beneficial effect in AN subjects.

Planned costs:

First step - 10.000 euros

5.000 euros - One scholarship for young researcher
5.000 euros - Reagents and consumable for research

Second step - 20.000 euros

10.000 euros - One scholarship for young researcher
10.000 euros - Reagents and consumable for research

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DONATION € 20.00

Pen-touch logo Universitiamo

DONATION € 50.00

Foulards logo Universitiamo

DONATION € 100.00

Acknowledgement in scientific papers and copy of the manuscript

DONATION € 500.00 OR MORE

The name of the donor will be reported in the scientific publication to be published with the results obtained

Team

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Maria Grazia Bottone

Dott.ssa | Founder

Maria Grazia Bottone

Dott.ssa | Founder

Researcher and head of the Laboratory of Cell Biology and Neurobiology, Department of Biology and Biotechnology, University of Pavia.

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Umberto Balottin

Prof.

Umberto Balottin

Prof.

Full Professor of child neuropsychiatry, University of Pavia, School of Medicine, Pavia, Italy.

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Maurizia Dossena

Dott.ssa

Maurizia Dossena

Dott.ssa
PhD in Neurobiology, researcher at the University of Pavia. Complete CV
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Violetta Insolia

Dott.ssa

Violetta Insolia

Dott.ssa
PhD student at Laboratory of Cellular Biology and Neurobiology, Department of Biology and Biotechnology, University of Pavia. Complete CV
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Daniela Buonocore

Dott.ssa

Daniela Buonocore

Dott.ssa

PhD in Biomedicine Sciences (curriculum of Pharmacology) - Post doc grant at the Pharmacology Laboratories of the Department of Biology and Biotechnology, University of Pavia.

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Manuela Verri

Dott.ssa

Manuela Verri

Dott.ssa

PhD in Neurobiology - Research Technician at the Pharmacology Laboratories of the Department of Biology and Biotechnology, University of Pavia.

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Matteo Alessio Chiappedi

Dott.

Matteo Alessio Chiappedi

Dott.
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Martina Maria Mensi

Dott.ssa

Martina Maria Mensi

Dott.ssa

Resident in Child and Adolescent Neurology and Psychiatry, University of Pavia, C. Mondino National Neurological Istitute.

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Eliana Antonaci

Dott.ssa

Eliana Antonaci

Dott.ssa
Resident in Child and Adolescent Neurology and Psychiatry, University of Pavia, C. Mondino National Neurological Istitute. Complete CV
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Sara Arnica

Dott.ssa

Sara Arnica

Dott.ssa
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Paola Veneroni

Paola Veneroni

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Chiara Rogantini

Student

Chiara Rogantini

Student

Medicine and Surgery’s student, thesis worker in C. Mondino National Neurological Institute - Child Neuropsychiatry Unit.

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Serena Camuso

Student

Serena Camuso

Student
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Beatrice Ferrari

Ph.D

Beatrice Ferrari

Ph.D
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Adele Andriulo

Dott.ssa

Adele Andriulo

Dott.ssa

Medical Director and Head of the Clinic Specialist Manager at "Casa di Cura Villa Esperia"

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Giulia Rancati

Dott.ssa

Giulia Rancati

Dott.ssa

Giulia Rancati is a Psychologist-Psychotherapist at the Nutritional rehabilitation and psychomotor of the obese patient Department of Villa Esperia in Salice Terme

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Backers

  1. Associazione Amici di Chiara
  2. Inner Wheel Club Oltrepò
  3. Ricavato Evento Arte e Anoressia, Aula Disegno - 8 aprile 2017
  4. Ricavato Evento vendita piantine aromatiche - 2 aprile 2017 Le Serre di Lorenzo Rivanazzano Terme
  5. Ricavato Partita di Calcio Benefica a Rivanazzano Terme - 1 aprile 2017
  6. Ricavato Evento Rotaract Voghera - 24 marzo 2017
  7. Lorenzo Rossi
  8. Ricavato Evento "Fame di cinema" del 24 marzo 2017 organizzato presso la Tenuta Montelio di Codevilla
  9. Leo Club Voghera, Circolo Tennis Voghera e CIF - evento 19 marzo 2017
  10. Elisa Elena Baracco
  11. Banca Centropadana Credito Cooperativo
  12. Anonymous
  13. Anonymous
  14. Anonymous
  15. Ricavato Festa di Primavera al Club House - 12 marzo 2017
  16. Istituto Comprensivo di Rivanazzano Terme
  17. Associazione "Occasioni di Festa" Rivanazzano Terme
  18. Lions Club Pavia Regisole
  19. Ricavato aperitivo benefico al Caffè Melograno 9 febbraio 2017
  20. carla marcella caramella
  21. Silvia Cipollina
  22. Maria Teresa Panigada
  23. Bergonzi Donata
  24. LORENZO CARMAGNOLI
  25. Rivanazzano Volley Club
  26. Claudia Alpini
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Enter your pledge amount

Contribute
  • Minimum Donation

  • Pen-touch logo Universitiamo

  • Foulards logo Universitiamo

  • Acknowledgement in scientific papers and copy of the manuscript

  • The name of the donor will be reported in the scientific publication to be published with the results obtained

Would you like to donate by bank transfer? click here


Would you like to donate more then 1600€ click here