The project

The aim of the project is to find advanced methodologies alternative to animal testing.

We are already working on the optimization of bioreactors for mimicking physiological systems instead of in vitro studies and animal models. These systems consist of inter-connected multi-organ culture chambers and they can be used for different cell lines or tissues, leading to the simulation of physiological barriers, and thus mimicking in vivo conditions.

By using this dynamic system, the bioactivity or toxicity of molecules (drugs, natural products, and nutraceuticals) can be tested. In addition, the adsorption and metabolism of single molecules and complex matrices (food, food supplements) could be evaluated. By mimicking in vivo processes, other pathologic conditions can be studied, like cancer cell adhesion to healthy tissues and metastasis formation in 3D culture models.

Our effors are aimed at investigating the described pathologic and physiologic mechanisms and, at the same time, at the implementation of a reliable in vitro model that will help us to spare unnecessary animal suffering and lives.


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Goals

1° goal: 5.000

Development of dynamic system useful for the study of new molecules potentially bioactive (for example anti-cancer and protective agents against tissue degeneration or bioactive food components) and toxic (drugs or toxic compound present in food). This system could be a good alternative to animal models

2° goal: 15.000

Grant for a young researcher

3° goal: 25.000

Up-grade of the dynamic model system

Sponsor

(Italiano) Westin Palace

Westin Palace Hotel

(Italiano) AIS Lombardia

Associazione Italiana Sommelier

Expert – Mortara

Expert di Mortara

Caffè Teatro di Pavia

Caffè Teatro di Pavia

Misana – Beer & Food

Misana - Beer & Food

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Rewards

Charitable contribution 50 €

Personalized unisex shopper with our logo

Charitable contribution 100 €

A personalized USB memory with our logo

Charitable contribution 200 €

A personalized gadget with our logo and a book

Charitable contribution 500 €

A personalized USB memory with our logo and a Smartbox gift (choise between Gourmet and Weelness)

Charitable contribution ≥ 1000€

A personalized USB memory with our logo, acknowledgements in our project scientific publications and shipping of an electronic copy of these publications

Team

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Adele Papetti

| Founder

Adele Papetti

| Founder
Assistant Professor Dept. of Drug Sciences, Lab Chief: Nutraceutical & Food Chem Toxicol Analysis Laboratory Complete CV
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Raffaella Colombo

Ricercatore confermato

Raffaella Colombo

Ricercatore confermato
Assistant Professor. Department of Drug Sciences, Medicinal Chemistry and Technology Section, University of Pavia. Complete CV
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Mayra Paolillo

Ricercatore confermato

Mayra Paolillo

Ricercatore confermato
Research Associate at the University of Pavia Complete CV
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Francesca Braschi

Laureata in Farmacia

Francesca Braschi

Laureata in Farmacia
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Virginia Pucci

Laureata in CTF

Virginia Pucci

Laureata in CTF
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Elena Arici

Laureanda in Farmacia

Elena Arici

Laureanda in Farmacia
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Laura Bugna

Laureanda in CTF

Laura Bugna

Laureanda in CTF
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Simona Franco

Laureanda in CTF

Simona Franco

Laureanda in CTF
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Flavia Gnecchi

Laureanda in Farmacia

Flavia Gnecchi

Laureanda in Farmacia
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Alessia Musco

Laureanda in Neurobiologia

Alessia Musco

Laureanda in Neurobiologia
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Desireé Portelli

Laureanda in Biotecnologie avanzate

Desireé Portelli

Laureanda in Biotecnologie avanzate
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Francesca Scopazzo

Laureanda in CTF

Francesca Scopazzo

Laureanda in CTF
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Lucia Ferron

Borsista

Lucia Ferron

Borsista
Scholar search-food chemistry laboratory - Pavia. Complete CV

Backers

  1. Anonymous
  2. Evento Beerburger e lotteria
  3. simona farci
  4. Maria Gabriella Pieranunzi
  5. Hotel Siesta Crissmass SRL
  6. Evento Libro Usato
  7. Evento aperitivo 23 maggio
  8. Alessandra Chiodo
  9. Anonymous
  10. Maria Chiara Dacco'
  11. Anonimo
  12. Anonymous
  13. Evento "AIS" Milano
  14. Evento "Raccolta con le Uova di Pasqua"
  15. Anonymous
  16. Roberta Viotti
  17. simona farci
  18. Marco Visconti
  19. franco lamensa
  20. Claudia Pastorino
  21. Anonymous
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Contribute
  • Donazione minima

  • Shopper unisex personalizzata con il nostro logo

  • Chiavetta USB personalizzata con il nostro logo

  • Chiavetta USB personalizzata con il nostro logo e un libro

  • Chiavetta USB personalizzata con il nostro logo e un cofanetto regalo Smartbox (Gourmet o Benessere, a scelta)

  • Chiavetta USB personalizzata con il nostro logo, ringraziamento nelle pubblicazioni scientifiche derivanti dal progetto e invio di una copia elettronica delle pubblicazioni stesse

Would you like to donate by bank transfer? click here


Would you like to donate more then 1600€ click here